Wegovy or Mounjaro? Your Questions Answered by Our Pharmacist

With more people exploring medical support for weight loss, two names keep coming up: Wegovy and Mounjaro. If you’ve been searching online for help or asking “Which is right for me?”, you’re not alone.

At Junction Pharmacy in Brixton, we support people at every stage of their weight loss journey. Whether you’re just starting to explore options or looking for alternatives after trying everything else, we’re here to help you make sense of the science—and the choices.

Here are answers to some of the most common questions we hear in clinic. If you’re curious about Wegovy vs Mounjaro, this guide is for you.

Q: Which helps you lose more weight—Wegovy or Mounjaro?

This is the most common question we get—and for good reason.

Both Wegovy (semaglutide) and Mounjaro (tirzepatide) have been shown to help with significant weight loss when combined with a healthy diet and regular physical activity. However, clinical trials suggest Mounjaro may lead to greater weight loss on average.

Wegovy is a GLP-1 receptor agonist, which helps regulate appetite and slow down digestion. Mounjaro is a dual agonist, meaning it activates both the GLP-1 and GIP receptors. This dual action may improve how the body regulates both insulin and hunger, leading to greater effects for some individuals.

That said, results vary from person to person. Your starting weight, metabolism, lifestyle, and medical history all play a role in how effective the medication will be.

Q: How are Wegovy and Mounjaro taken?

Both medications are administered as once-weekly injections, which you can do yourself at home using a pre-filled pen.

Wegovy is taken in gradually increasing doses over a few weeks until you reach a maintenance dose.

Mounjaro also has a dose-escalation plan but offers multiple final dose options, allowing more flexibility based on how your body responds.

Our pharmacists will guide you through the injection technique and support you through the titration schedule.

Q: Are they safe for long-term use?

Yes, when used under medical supervision, both Wegovy and Mounjaro have been shown to be safe and effective in long-term studies.

However, like all medications, they’re not suitable for everyone. They may not be recommended if you have certain health conditions such as pancreatitis, thyroid problems, or if you’re pregnant or breastfeeding.

Regular check-ins and monitoring are part of our weight loss service, so we can ensure the medication remains suitable and safe for you over time.

Q: What are the main side effects?

The most common side effects of both medications are gastrointestinal and usually mild to moderate in severity. These include:

• Nausea

• Constipation

• Diarrhoea

• Bloating

• Heartburn

These symptoms are more likely to occur in the early stages of treatment and often improve as your body adjusts.

More serious side effects are rare but can include pancreatitis, gallbladder issues, or allergic reactions. Our team will talk you through the risk factors before you start, and we’re always here if you experience anything unusual.

Q: Can I still lose weight without injections?

Absolutely. Not everyone needs medication to lose weight, and we’ll never push you towards something that isn’t right for you. For some people, lifestyle changes and consistent support are enough to see great results.

But for others—especially those with weight-related health concerns, a high BMI, or a history of struggling to keep weight off—medication can be a valuable extra tool. It’s not about replacing diet and exercise; it’s about giving your body the support it needs to help you stay on track.

Q: How do I know if I qualify for treatment?

When you book a consultation with us, our pharmacist will assess your medical history, current weight, BMI, and lifestyle to determine if you’re eligible for treatment. We’ll also help you understand what to expect and decide if it’s the right path for you.

Generally, these medications are offered to people with a BMI over 30, or over 27 with other health conditions such as high blood pressure, type 2 diabetes, or sleep apnoea.

Every Weight Loss Journey Is Different

When it comes to Wegovy vs Mounjaro, there’s no one-size-fits-all answer. The best choice depends on your personal goals, how your body responds, and whether you’re managing any other health conditions.

At Junction Pharmacy in Brixton, we offer both Wegovy and Mounjaro as part of our pharmacist-led weight management clinic. Our goal is to provide safe, compassionate care—whether you’re starting out, restarting, or looking for something that finally works.

If you’re wondering whether weight loss medication is right for you, reach out to book a consultation with our team. We’re here to listen, advise, and guide you through your options—with no pressure, no judgement, and no fads.

This blog was written on behalf of Junction Pharmacy by Pharmacy Mentor.